How can i Install a Game on to E drive in stead of the C drive.?

If the game has the option, just enter advanced installation and change the install path. If that doesn't work, try to clean some space on C:, let it install there, then move it to E: like the other user suggested. Note that when doing this, you will have to change the paths of any shortcuts the installer added so that clicking on the shortcut does not lead you to a not found error.